Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency
Abstract Background The persistence of latent HIV-1 reservoirs is the principal barrier preventing the eradication of HIV-1 infection in patients by current antiretroviral therapy.It is thus crucial to understand the molecular mechanisms involved in the establishment, maintenance and reactivation of HIV-1 latency.Since chromatin remodeling has been